What Is A Liposome?

A liposome is a minute-sized vesicle that is artificially produced. It is round in shape and is made from natural phospholipids and cholesterol. The credit for discovering liposomes goes to Dr. Alec Bangham. Dr. Bangham accidentally found liposomes when he was conducting a study on blood clotting and phospholipids. During the course of his studies, Dr. Bangham found that phospholipids combine with water to form a miniscule bi-layered sphere.

Under natural circumstances, phospholipids are present in stable membranes. When these membranes are disturbed in an aqueous solution, the phospholipids form tiny pouches with bi-layers. These bi-layered pouches are known as liposomes.

Phospholipids consist of molecules that have a head and tail. The head part of the molecule has an affinity to water, while the tail pushes away from water. When phospholipids combine with water, the heads of the molecules realign themselves to face the water, while the tails face away from the water. The same story occurs inside th

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